Warning: Your current browser has not been tested extensively with this website, which may result in some some errors with functionality. The following browsers are fully supported:

Please use a different browser.

Available studies (70 found)

Short citationFull citationBioassayEpidemiologyEpi. meta-analysisIn vitroEcology
Hannas et al. 2011b Hannas BR et al. Dose-response assessment of fetal testosterone production and gene expression levels in rat testes following in utero exposure to diethylhexyl phthalate, diisobutyl phthalate, diisoheptyl phthalate, and diisononyl phthalate. Toxicol. Sci. 2011; 123 (1):206-16. PubMed DOI
Hannas et al. 2012 Hannas BR et al. Genomic biomarkers of phthalate-induced male reproductive developmental toxicity: a targeted RT-PCR array approach for defining relative potency. Toxicol. Sci. 2012; 125 (2):544-57. PubMed DOI
Howdeshell et al. 2008 Howdeshell KL et al. A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner. Toxicol. Sci. 2008; 105 (1):153-65. PubMed DOI
Jarfelt et al. 2005 Jarfelt K et al. Antiandrogenic effects in male rats perinatally exposed to a mixture of di(2-ethylhexyl) phthalate and di(2-ethylhexyl) adipate. Reprod. Toxicol. ; 19 (4):505-15. PubMed
Jiang et al. 2007 Jiang J et al. Study on developmental abnormalities in hypospadiac male rats induced by maternal exposure to di-n-butyl phthalate (DBP). Toxicology 2007; 232 (3):286-93. PubMed
Johnson et al. 2007 Johnson KJ et al. Mapping gene expression changes in the fetal rat testis following acute dibutyl phthalate exposure defines a complex temporal cascade of responding cell types. Biol. Reprod. 2007; 77 (6):978-89. PubMed
Johnson et al. 2011 Johnson KJ et al. Species-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathways. Toxicol. Sci. 2011; 120 (2):460-74. PubMed DOI
Jones et al. 2015 Jones S et al. In utero exposure to di-(2-ethylhexyl) phthalate induces testicular effects in neonatal rats that are antagonized by genistein cotreatment. Biol. Reprod. 2015; 93 (4):92. PubMed DOI
Kim et al. 2010 Kim TS et al. Effects of in utero exposure to DI(n-Butyl) phthalate on development of male reproductive tracts in Sprague-Dawley rats. J. Toxicol. Environ. Health Part A 2010; 73 (21-22):1544-59. PubMed DOI
Klinefelter et al. 2012 Klinefelter GR et al. Novel molecular targets associated with testicular dysgenesis induced by gestational exposure to diethylhexyl phthalate in the rat: a role for estradiol. Reproduction 2012; 144 (6):747-61. PubMed DOI
Kuhl et al. 2007 Kuhl AJ, Ross SM, and Gaido KW. CCAAT/enhancer binding protein beta, but not steroidogenic factor-1, modulates the phthalate-induced dysregulation of rat fetal testicular steroidogenesis. Endocrinology 2007; 148 (12):5851-64. PubMed
L. Li et al. 2015 Li L et al. Inutero exposure to diisononyl phthalate caused testicular dysgenesis of rat fetal testis. Toxicol. Lett. 2015; 232 (2):466-74. PubMed DOI
Lee et al. 2004 Lee KY et al. Diverse developmental toxicity of di-n-butyl phthalate in both sexes of rat offspring after maternal exposure during the period from late gestation through lactation. Toxicology 2004; 203 (1-3):221-38. PubMed
Lehmann et al. 2004 Lehmann KP et al. Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate. Toxicol. Sci. 2004; 81 (1):60-8. PubMed
Li et al. 2009 Li Y et al. Neurobehavioral toxicity study of dibutyl phthalate on rats following in utero and lactational exposure. J Appl Toxicol 2009; 29 (7):603-11. PubMed DOI
Li et al. 2013 Li M et al. Dose-related effect by maternal exposure to di-(2-ethylhexyl) phthalate plasticizer on inducing hypospadiac male rats. Environ. Toxicol. Pharmacol. 2013; 35 (1):55-60. PubMed DOI
Lin et al. 2008 Lin H et al. Involvement of testicular growth factors in fetal Leydig cell aggregation after exposure to phthalate in utero. Proc. Natl. Acad. Sci. U.S.A. 2008; 105 (20):7218-22. PubMed DOI
Lin et al. 2009 Lin H et al. In utero and lactational exposures to diethylhexyl-phthalate affect two populations of Leydig cells in male Long-Evans rats. Biol. Reprod. 2009; 80 (5):882-8. PubMed DOI
Liu et al. 2008 Liu X et al. Di(2-ethylhexyl) phthalate (DEHP) increases transforming growth factor-beta1 expression in fetal mouse genital tubercles. J. Toxicol. Environ. Health Part A 2008; 71 (19):1289-94. PubMed DOI
Macleod et al. 2010 Macleod DJ et al. Androgen action in the masculinization programming window and development of male reproductive organs. Int. J. Androl. 2010; 33 (2):279-87. PubMed DOI
Mahood et al. 2007 Mahood IK et al. In utero exposure to di(n-butyl) phthalate and testicular dysgenesis: comparison of fetal and adult end points and their dose sensitivity. Environ. Health Perspect. 2007; 115 Suppl 1 ():55-61. PubMed DOI
Martino-Andrade et al. 2009 Martino-Andrade AJ et al. Coadministration of active phthalates results in disruption of foetal testicular function in rats. Int. J. Androl. 2009; 32 (6):704-12. PubMed DOI
Masutomi et al. 2003 Masutomi N et al. Impact of dietary exposure to methoxychlor, genistein, or diisononyl phthalate during the perinatal period on the development of the rat endocrine/reproductive systems in later life. Toxicology 2003; 192 (2-3):149-70. PubMed
McKinnell et al. 2009 McKinnell C et al. Effect of fetal or neonatal exposure to monobutyl phthalate (MBP) on testicular development and function in the marmoset. Hum. Reprod. 2009; 24 (9):2244-54. PubMed DOI
Moore et al. 2001 Moore RW et al. Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer Di(2-ethylhexyl) phthalate. Environ. Health Perspect. 2001; 109 (3):229-37. PubMed

Showing studies 26-50 of 70