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PFOA/PFOS Exposure and Immunotoxicity (2016)
Literature review
Study list
Risk of bias
Endpoint list
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Home
Assessments
PFOA/PFOS Exposure and Immunotoxicity (2016)
Literature review
Study list
Risk of bias
Endpoint list
Visualizations
Downloads
About
Resources
Public Assessments
PFOA/PFOS Exposure and Immunotoxicity (2016)
Endpoints
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Assessment endpoints (2975 found)
Endpoint name
Ordering
↑ study
↑ experiment name
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↑ endpoint name
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Study reference
ex: Smith et al. 2010
Chemical name
ex: sodium
CAS
ex: 107-02-8
Lifestage exposed
ex: pup
Lifestage assessed
ex: adult
Species
---------
ex: Mouse
Strain
---------
ex: B6C3F1
Sex
Male
Female
Combined
Not reported
Data extracted
All data
Yes
No
System
ex: endocrine
Organ
ex: pituitary
Effect
ex: alanine aminotransferase (ALT)
Effect Subtype
ex:
Tags
ex: antibody response
Dose units
---------
ppm
mg/kg-day
mg/kg
mg/kg TAD
%
mg/L
mg ion/kg egg
mg/kg-day ADD
mg/kg food
mg/kg egg
mmol/kg-day
mg/kg bw
mg/mL
ng/g w/w
ug/mL serum
g/kg bw
g/kg TAD
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Study
Experiment
Animal group
Endpoint
Units
NOEL
LOEL
BMD
BMDL
DeWitt 2015
81434
Dose-response
764
Female C57BL/6N mice
1613
IgM antibody titer (DNP)
16094
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
765
Female C57BL/6N mice
1614
spleen cellularity
16095
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
766
Female C57BL/6N mice
1615
spleen cellularity
16096
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
767
Female C57BL/6N mice
1616
spleen cellularity
16097
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
765
Female C57BL/6N mice
1614
spleen B220+ cells
16102
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
766
Female C57BL/6N mice
1615
spleen B220+ cells
16103
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
767
Female C57BL/6N mice
1616
spleen B220+ cells
16104
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
765
Female C57BL/6N mice
1614
spleen CD4+ cells
16105
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
766
Female C57BL/6N mice
1615
spleen CD4+ cells
16106
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
767
Female C57BL/6N mice
1616
spleen CD4+ cells
16107
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
765
Female C57BL/6N mice
1614
spleen CD8+ cells
16108
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
766
Female C57BL/6N mice
1615
spleen CD8+ cells
16109
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
767
Female C57BL/6N mice
1616
spleen CD8+ cells
16110
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
765
Female C57BL/6N mice
1614
spleen DP (CD4+/CD8+) cells
16111
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
766
Female C57BL/6N mice
1615
spleen DP (CD4+/CD8+) cells
16112
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
767
Female C57BL/6N mice
1616
spleen DP (CD4+/CD8+) cells
16113
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
765
Female C57BL/6N mice
1614
spleen DN (CD4-/CD8-) cells
16114
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
766
Female C57BL/6N mice
1615
spleen DN (CD4-/CD8-) cells
16115
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
767
Female C57BL/6N mice
1616
spleen DN (CD4-/CD8-) cells
16116
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
765
Female C57BL/6N mice
1614
spleen NK 1.1 cells
16117
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
766
Female C57BL/6N mice
1615
spleen NK 1.1 cells
16118
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response (SRBC)
767
Female C57BL/6N mice
1616
spleen NK 1.1 cells
16119
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
763
Female PPARα KO mice
1612
body weight
16129
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
763
Female C57BL/6-Tac (wild-type) mice
1611
body weight
16131
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
763
Female C57BL/6-Tac (wild-type) mice
1611
thymus: relative weight
16133
ppm
-
-
-
-
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Showing endpoints
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