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PFOA/PFOS Exposure and Immunotoxicity (2016)
Literature review
Study list
Risk of bias
Endpoint list
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Home
Assessments
PFOA/PFOS Exposure and Immunotoxicity (2016)
Literature review
Study list
Risk of bias
Endpoint list
Visualizations
Downloads
About
Resources
Public Assessments
PFOA/PFOS Exposure and Immunotoxicity (2016)
Endpoints
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Assessment endpoints (2975 found)
Endpoint name
Ordering
↑ study
↑ experiment name
↑ animal group
↑ endpoint name
↑ system
↑ organ
↑ effect
↑ effect subtype
↑ chemical
How results will be ordered
Items per page
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×
Study reference
ex: Smith et al. 2010
Chemical name
ex: sodium
CAS
ex: 107-02-8
Lifestage exposed
ex: pup
Lifestage assessed
ex: adult
Species
---------
ex: Mouse
Strain
---------
ex: B6C3F1
Sex
Male
Female
Combined
Not reported
Data extracted
All data
Yes
No
System
ex: endocrine
Organ
ex: pituitary
Effect
ex: alanine aminotransferase (ALT)
Effect Subtype
ex:
Tags
ex: antibody response
Dose units
---------
ppm
mg/kg-day
mg/kg
mg/kg TAD
%
mg/L
mg ion/kg egg
mg/kg-day ADD
mg/kg food
mg/kg egg
mmol/kg-day
mg/kg bw
mg/mL
ng/g w/w
ug/mL serum
g/kg bw
g/kg TAD
Cancel
Study
Experiment
Animal group
Endpoint
Units
NOEL
LOEL
BMD
BMDL
DeWitt 2009
57621
Sham-operated
520
Female C57BL/6n mice
570
triglycerides
8604
ppm
-
-
-
-
DeWitt 2009
57621
Sham-operated
520
Female C57BL/6n mice
570
total protein
8605
ppm
-
-
-
-
DeWitt 2009
57621
Sham-operated
520
Female C57BL/6n mice
570
lactate dehydrogenase (LDH)
8606
ppm
-
-
-
-
DeWitt 2009
57621
Sham-operated
520
Female C57BL/6n mice
570
corticosterone
8607
ppm
-
-
-
-
DeWitt 2009
57621
Sham-operated
520
Female C57BL/6n mice
570
water consumption
8608
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
IgM antibody titer (SRBC)
8609
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
body weight
8610
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
alkaline phosphatase (ALP)
8611
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
alanine aminotransferase (ALT)
8612
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
aspartate aminotransferase (AST)
8613
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
sorbitol dehydrogenase (SDH)
8614
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
blood urea nitrogen (BUN)
8615
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
creatinine
8616
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
gamma-glutamyl transpeptidase (GGT)
8617
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
blood: glucose
8618
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
cholesterol
8619
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
triglycerides
8620
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
total protein
8621
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
lactate dehydrogenase (LDH)
8622
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
corticosterone
8623
ppm
-
-
-
-
DeWitt 2009
57621
Adrenalectomized
521
Female C57BL/6n mice
571
water consumption
8624
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
763
Female C57BL/6-Tac (wild-type) mice
1611
spleen: relative weight
16090
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
763
Female PPARα KO mice
1612
spleen: relative weight
16091
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
763
Female C57BL/6-Tac (wild-type) mice
1611
IgM antibody titer (SRBC)
16092
ppm
-
-
-
-
DeWitt 2015
81434
Dose-response
763
Female PPARα KO mice
1612
IgM antibody titer (SRBC)
16093
ppm
-
-
-
-
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Showing endpoints
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of
2975