Supplemental Figure 06. Estrogen Receptor Binding Assays

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Assays run in agonist mode are shown in red text, assays run in antagonist mode are shown in black text. Solid lines separate different chemicals.


Not shown in this figure:

  • Akahori et al. 2008 only presented log relative binding affinities (Estradiol log(RBA)=2.00)
  • 4,4-Bisphenol F log(RBA)=-1.14
  • Bisphenol AF log(RBA)=-0.11
  • Bisphenol S log(RBA)=-2.26
  • Bisphenol Z log(RBA)=-0.67
  • Yamasaki et al. 2004 only presented relative binding affinity as ratio of IC50 values compared to E2
  • 4,4-Bisphenol F 0.0719% of E2
  • Bisphenol S 0.0055% of E2
  • Bishpenol Z 0.212% of E2
  • Yamasaki et al. 2003apresented relative binding affinity as ratio of IC50 values compared to E2 (100%)
  • Bisphenol AF 0.774% of E2
  • Coleman et al. 2003 presented relative binding affinity as ratio of IC50 values compared to E2 (100%)
  • 4,4-Bisphenol F 0.09% of E2
  • Bisphenol A 0.32% of E2
  • Bisphenol AF 2.62% of E2
  • Bisphenol AP 1.66% of E2
  • Bisphenol B 1.91% of E2
  • Bisphenol C 1.68% of E2
  • Bisphenol E 0.1% of E2
  • Bisphenol Z 4.98% of E2
  • TMBPA 0.21% of E2