Lee et al., 2011
Risk of bias
Animal bioassay experiments
| Name | Type | Comments |
|---|---|---|
| Tumor-prone mice/animals | Chronic (>90 days) | 2W/kg CDMA and WDMA each = 4 W/kg av body "Here, carcinogenic effects of combined signal RF-EMFs on AKR/J mice, which were used for the lymphoma animal model, were investigated. Six-week-old AKR/J mice were simul?taneously exposed to two types of RF signals: single code division multiple access (CDMA) and wideband code division multiple access (WCDMA). AKR/J mice were exposed to combined RF?EMFs for 45 min/day, 5 days/week, for a total of 42 weeks. The whole-body average specific absorption rate (SAR) of CDMA and WCDMA fields was 2.0 W/kg each, 4.0 W/kg in total. When we examined final survival, lymphoma incidence, and splenomegaly incidence, no differ?ences were found between sham- and RF-exposed mice. However, occurrence of metastasis infil?tration to the brain in lymphoma-bearing mice was significantly different in RF-exposed mice when compared to sham-exposed mice, even though no consistent correlation (increase or decrease) was observed between male and female mice. However, infiltration occurrence to liver, lung, and spleen was not different between the groups. From the results, we suggested that simul?taneous exposure to CDMA and WCDMA RF-EMFs did not affect lymphoma development in AKR/J mice." |