Anderson-Mahoney 2008

Data type(s)Epidemiology
Full citationAnderson-Mahoney P, Kotlerman J, Takhar H, Gray D, and Dahlgren J. 2008. Self-reported health effects among community residents exposed to perfluorooctanoate. New Solut 18(2): 129-143.
AbstractSerious health effects due to perfluorooctanoate (PFOA) exposure are suspected. The aim of this study was to evaluate the health status of nearby residents, with prolonged exposure to PFOA in their drinking water. A population of 566 white residents who were plaintiffs or potential plaintiffs in a lawsuit was evaluated by questionnaire for health history and symptoms. Standardized Prevalence Ratios were estimated using National Health and Examination Survey (NHANES) data files for comparison rates. The exposed subjects reported statistically significant greater prevalence of angina, myocardial infarction, and stroke (SPR=8.07, 95% C.I.=6.54-9.95; SPR=1.91, 95% C.I.=1.40-2.62, and SPR=2.17, 95% C.I.=1.47-3.21, respectively), chronic bronchitis, shortness of breath on stairs, asthma (SPR=3.60, 95% C.I.=2.92-4.44; SPR=2.05, 95% C.I.=1.70-2.46; SPR=1.82, 95% C.I.=1.47-2.25, respectively), and other serious health problems. The increased prevalence of adverse health effects may be due to PFOA. Further study is needed.
Reference hyperlink
Literature review tagsHuman Study
COI reportedNot reported
Funding sourceLaw firms - potential COI due to PFOA litigation. Law firms states they were not involved with data analysis, interpretaion, or writing and "legal case settled prior to submission of manuscript" See NOTES
Study identifier(Anderson-Mahoney 2008)
Author contacted?
Summary/extraction commentsData extracted:
  • TABLE 2 - chronic bronchitis, shortness of breath, asthma
  • TABLE 3 - asthma, chronic bronchitis, shortness of breath climbing stairs

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Epidemiological study populations