Housing conditions and husbandry practices should be identical across control and experimental groups because these variables may impact the outcome of interest. Identical conditions include use of the same vehicle in control and experimental animals and the rating for this risk-of-bias element will depend largely on the consistent use vehicle across treatment groups. That is because under current reporting practices it is unlikely that similarity of conditions will be explicitly reported in most animal studies. Thus, we will assume unless stated otherwise that experimental conditions (other than treatment vehicle) were identical across groups.

Name	Type	Comments
PPARalpha-Null Mice	Short-term (1-30 days)
WildType Mice	Short-term (1-30 days)

Yang 2002a

Risk of bias

Animal bioassay experiments

HAWC