Male Wistar rats were obtained from the breeding colony of the National Vertinary Research Institute (NVRI), Jos, Nigeria. The animals were kept in the animal holding facility of the Department of Anatomy, Bingham University, Nasarawa, Nigeria. They were given standard rat pellets and water ad libitum and were allowed to acclimatize for two weeks. They were kept in aerated cages under standard laboratory conditions of 12 h light/dark cycle (lights on at 0800 h) and average room temperature (22 ± 2 ◦C; relative humidity, 50–60%). All experimental protocols were followed upon approval by the local institutional research committee and in accordance with the guidelines for animal research, as detailed in the NIH guidelines for the care and use of laboratory animals [22].