| ICR mouse water |
Subchronic (30-90 days) |
Animals were randomly placed into four groups: the control group (n = 8), the low fluoride group (n = 7), the moderate fluoride group (n =7) and the high fluoride group (n = 6), which were respectively given free access to distilled water or 1 mg/L, 5 mg/L, or 10 mg/L aqueous sodium fluoride solution for the ten-week experimental period.; This study used 28 one-month-old ICR white mice supplied by the Laboratory Animal Breeding Center of the Jinghua Pharmaceutical Testing Facility. |