He 1989 [translated in He 2008]
| Data type(s) | Epidemiology |
|---|---|
| Full citation | He H, Cheng ZS, Liu WQ. 1989. [Effects of fluorine on the human fetus]. J Control Endem Dis 4(3): 136-138. |
| Abstract | In an endemic fluorosis area, 16 fetuses that were delivered during their sixth to eighth month of gestation by means of artificial abortion were collected and studied. The results [compared to 10 control fetuses from a non-endemic area] show that fluorine levels in tissues are obviously high, especially in brain, calvarium, and femur. The activity of alkaline phosphatase in femur and kidney was raised. By observation of the ultrastructure of samples, the number of mitochondria, rough-surfaced endoplasmic reticulum, and free ribosome in neurons of cerebral cortex were reduced, and the rough-surfaced endoplasmic reticulum was obviously dilated. These findings indicate that the neurons of the cerebral cortex in the developing brain may be one of the targets of fluorine. |
| Literature review tags | Human Study |
| COI reported | Authors report they have no COI |
| Study identifier | He 2008 |
| Author contacted? | false |
| Author contact details | Article was translated from Chinese, but no author contact information was available. |
| Summary/extraction comments | Cerebral cortex histopathology (qualitative) Translated from original Chinese (1989) and published in volume 41 of the journal Fluoride in 2008: He H, Cheng ZS, Liu WQ. 2008. Effects of fluorine on the human fetus. Fluoride 41: 321-326. |
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