NTP 2018 (rat)

Risk of bias

Animal bioassay experiments

NameTypeComments
Chronic bioassay Chronic (>90 days)

F0 was exposed GD5 at 1.5, 3, 6 W/kg or sham-exposed for 18 hrs and 20 min/d. Subsequently, the F1 generation, male and female rats were exposed at CDMA 0, 1.5, 3, 6 W/kg, 7d/wk for 104 weeks total.


Note that only the following cancer end parameters were extracted:

  • survival
  • body weight
  • brain
  • heart
  • adrenals
  • liver
  • pituitary
Chronic bioassay Chronic (>90 days)

F0 was exposed GD5 at 1.5, 3, 6 W/kg or sham-exposed for 18 hrs and 20 min/d. Subsequently, the F1 generation, male and female rats were exposed at GSM 0, 1.5, 3, 6 W/kg, 7d/wk for 104 weeks total.


Note that only the following cancer end parameters were extracted:

  • survival
  • body weight
  • brain
  • heart
  • adrenals
  • pituitary
  • prostate (male rats)
  • kidney
  • thyroid gland
  • pancreas