thymus: absolute weight

Endpoint Details

Endpoint namethymus: absolute weight
Systemimmune and lymphatic system
Organthymus
Effectabsolute weight
Observation time49 days
Additional tags
Data reported?
Data extracted?
Values estimated?
Location in literatureAppendix 1 from complete study report (publication only stated not significant)
NOEL30 mg/kg-day
MonotonicityN/A, single dose level study
Statistical test descriptionANOVA; Dunnett's test
Power notes"underpowered to detect a change of 10% control" (sample size <50% of recommended) [calculated n=67; mean required-N calculation from all dose-groups] "underpowered to detect a change of 20% control" (sample size is 50% to <75% of recommended) [calculated n=18; mean required-N calculation from all dose-groups]

Dataset

Dose (mg/kg-day)Number of AnimalsResponse (g)Standard Deviation
a NOEL (No observed effect level)
0100.3450.076
30a100.3220.06

Plot

0510152025300.280.300.320.340.360.380.40Dose = 0 mg/kg-day N = 10 Response = 0.345 g Standard Deviation = 0.076Dose = 30 mg/kg-day N = 10 Response = 0.322 g Standard Deviation = 0.06Dose (mg/kg-day)Response (g)thymus: absolute weightDosesNOEL