| Endpoint name | spleen: absolute weight |
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| System | immune and lymphatic system |
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| Organ | spleen |
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| Effect | absolute weight |
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| Observation time | 30 days |
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| Additional tags | |
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| Data reported? | true |
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| Data extracted? | true |
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| Values estimated? | false |
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| Location in literature | Table 2 |
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| NOEL | 30 mg/kg-day |
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| Monotonicity | N/A, single dose level study |
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| Statistical test description | ANOVA with post hoc Tukey's test and the least squares means t-test with Tukey's adjustment |
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| Trend result | not reported |
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| Power notes | "underpowered to detect a change of 10% control" (sample size <50% of recommended) [calculated n=52; mean required-N calculation from all dose-groups]
"underpowered to detect a change of 20% control" (sample size is 75% to <100% of recommended) [calculated n=14; mean required-N calculation from all dose-groups] |
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