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PFOA/PFOS Exposure and Immunotoxicity (2016)
Literature review
Study list
Risk of bias
Endpoint list
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Home
Assessments
PFOA/PFOS Exposure and Immunotoxicity (2016)
Literature review
Study list
Risk of bias
Endpoint list
Visualizations
Downloads
About
Resources
Public Assessments
PFOA/PFOS Exposure and Immunotoxicity (2016)
Endpoints
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Assessment endpoints (12 found)
Endpoint name
Ordering
↑ study
↑ experiment name
↑ animal group
↑ endpoint name
↑ system
↑ organ
↑ effect
↑ effect subtype
↑ chemical
How results will be ordered
Items per page
25 per page
50 per page
100 per page
250 per page
500 per page
×
Study reference
ex: Smith et al. 2010
Chemical name
ex: sodium
CAS
ex: 107-02-8
Lifestage exposed
ex: pup
Lifestage assessed
ex: adult
Species
---------
ex: Mouse
Strain
---------
ex: B6C3F1
Sex
Male
Female
Combined
Not reported
Data extracted
All data
Yes
No
System
ex: endocrine
Organ
ex: pituitary
Effect
ex: alanine aminotransferase (ALT)
Effect Subtype
ex:
Tags
Secondary IgG
ex: antibody response
Dose units
---------
ppm
mg/kg-day
mg/kg
mg/kg TAD
%
mg/L
mg ion/kg egg
mg/kg-day ADD
mg/kg food
mg/kg egg
mmol/kg-day
mg/kg bw
mg/mL
ng/g w/w
ug/mL serum
g/kg bw
g/kg TAD
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Study
Experiment
Animal group
Endpoint
Units
NOEL
LOEL
BMD
BMDL
DeWitt 2008
57611
Single dose-level
444
Female C57BL/6J mice
566
IgG antibody titer (SRBC)
8546
ppm
-
-
-
-
DeWitt 2008
57611
Recovery study - 20days
445
Female C57BL/6J mice
567
IgG antibody titer (SRBC)
8560
ppm
-
-
-
-
DeWitt 2008
57611
Dose-response high
446
Female C57BL/6n mice
568
IgG antibody titer (SRBC)
8574
ppm
-
-
-
-
DeWitt 2008
57611
Dose-response low
447
Female C57BL/6n mice
569
IgG antibody titer (SRBC)
8588
ppm
-
-
-
-
Dong 2011
57605
Dose-response
471
Male C57BL/6 mice
584
IgG antibody titer (SRBC)
8832
ppm
-
-
-
-
Dong 2011
57605
Dose-response
471
Male C57BL/6 mice
584
IgG1 antibody titer (SRBC)
8833
ppm
-
-
-
-
Dong 2011
57605
Dose-response
471
Male C57BL/6 mice
584
IgG2a antibody titer (SRBC)
8834
ppm
-
-
-
-
Lefebvre 2008
57618
Dose-response
437
Male Sprague-Dawley rat
594
IgG antibody titer (KLH)
9017
ppm
-
-
-
-
Lefebvre 2008
57618
Dose-response
437
Female Sprague-Dawley rat
595
IgG antibody titer (KLH)
9053
ppm
-
-
-
-
Peden-Adams 2009
57622
In ovo exposure
522
White leghorn chicken bird (F1)
596
IgM and IgY antibody titer (SRBC)
9091
ppm
-
-
-
-
Peden-Adams 2009
57622
In ovo exposure
522
White leghorn chicken bird (F1)
596
IgY antibody titer (SRBC)
9093
ppm
-
-
-
-
Smits and Nain 2013
57657
Dose-response
478
Male Japanese quail
685
IgY antibody titer (DNP-KLH)-2*
10566
ppm
10.0
-
-
-