Female BALB/c mice

Available endpoints

↑ Endpoint Organ Obs. TimeDose [mg/kg-day]
0520
N--333
percentage of apoptotic cells in thymusthymus14 days3.77 ± 1.0054.53 ± 1.005 (20%)a4.94 ± 1.905 (31%)
N--888
spleen: relative weightspleen14 days0.418 ± 0.1130.34 ± 0.141 (-19%)a0.255 ± 0.057 (-39%)b,c
thymus: relative weightthymus14 days0.304 ± 0.170.251 ± 0.141 (-17%)a0.167 ± 0.17 (-45%)b,c
a NOEL (No observed effect level)
b Significantly different from control (p < 0.05)
c LOEL (Lowest observed effect level)

Additional endpoints

Endpoints which have no dose-response data extracted.